• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

DNA2 inhibitor C5

CAS No. 35973-25-2

DNA2 inhibitor C5 ( —— )

产品货号. M24317 CAS No. 35973-25-2

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥624 有现货
5MG ¥988 有现货
10MG ¥1604 有现货
25MG ¥3686 有现货
50MG ¥5443 有现货
100MG ¥7744 有现货
500MG ¥15552 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    DNA2 inhibitor C5
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM).
  • 产品描述
    DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    DNA2 nuclease
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    35973-25-2
  • 分子量
    234.2
  • 分子式
    C10H6N2O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:31.25 mg/mL (133.45 mM; Need ultrasonic)
  • SMILES
    O=C(C1=C(O)C2=CC=CC([N+]([O-])=O)=C2N=C1)O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Binghui Shen, et al. Dna2 inhibitors for cancer treatment. US20170226063A1.
产品手册
关联产品
  • Methyl nomilinate

    Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.

  • Kaempferol 3,7-di-O-...

    Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective activity and can slow down differentiated neuronal cells SH-SY5Y from Amyloid β peptide-induced damage.

  • Isoliensinine

    Isoliensinine, a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities.